What is a KRAS mutation?
The KRAS (pronounced kay-ras) protein signals our cells when to grow and also when to stop growing. Everyone has this protein in their bodies.1,2
So, what is KRAS G12C?
KRAS G12C is a mutation that changes the KRAS protein, causing uncontrollable cell growth and tumors.3
KRAS G12C is one of the most common biomarkers. In fact, approximately 1 in 8 people with non-small cell lung cancer (NSCLC) have the KRAS G12C mutation.4
Biomarker definitionsHow can I learn more about
biomarkers?
If you’ve had a biomarker test, ask your doctor about the results.
If they don’t have your results, ask about getting a test.
Connect with people
who share your
biomarker status.
References: 1. NCI Dictionary of Cancer Terms. Cancer.gov. Accessed January 23, 2023. 2. Ryan MB, Corcoran RB. Nat Rev Clin Oncol. Vol 15. 2018. 3. Hong DS, et al. N Engl J Med. 2020. 4. Data on file, Amgen, 2022. Amgen [Analysis of AACR Genie v12-2022 (v5.0)].
